Scientist, Mammalian Cell Culture, Process Development
About Ambrx:
Ambrx, Inc. is a biopharmaceutical company with a mission to deliver breakthrough protein therapeutics using an expanded genetic code. Unlike conventional conjugation techniques that create a mixture of suboptimal molecules, Ambrx technology combines site specific conjugation with proprietary linkers, payloads and pharmacokinetic extenders to create a single molecular species that is optimized for safety, efficacy and biophysical properties. We call this process Protein Medicinal Chemistry
Ambrx is seeking a highly-motivated Scientist I/II to be a key member of a fast-paced and dynamic organization.
Responsibilities:
Responsible for developing cell culture medium, feeding strategies, process parameter optimization, and scale-up to support R&D, large scale production, pre-clinical, and clinical activities.
Participates in writing development reports, protocols, batch records and technology transfer.
Must demonstrate strong scientific/technical and interpersonal skills as well as the ability to communicate effectively.
Applies biological and engineering expertise to develop recombinant protein production processes suitable for large-scale cGMP manufacturing and acts as a mentor for those with similar or less engineering expertise, providing both technical expertise and leadership to understand potential career paths.
This job may require some travel to development partners and other manufacturing sites both in and outside the US. PhD with a minimum of 1
year(s) or Master's Degree with a minimum 8
years industrial experience and a degree in Chemical Engineering or related field.
Must have hands on experience in process development utilizing CHO cells to produce biologics using spin tubes, shake flasks, and bioreactors
Knowledgeable in cell culture process scale-up and technology transfer to contract manufacturing organizations.
Must have a proven record of innovation
Must have the ability to apply scientific and engineering principles to solve complex problems.
Must have a good understanding of cell physiology, metabolism, and cell biology
Must have the ability to multitask and adapt in a fast paced environment and stay focused on project deliverables.
Work with minimum supervision in designing and executing experiments and analyzing data.
Additional Desired Experience and Skills:
Knowledge of Design of Experiments (DOE) and statistical analysis of data.
Working knowledge of GMPs and experience writing SOPs and batch records.
Medium development experience for CHO cell culture
Experience with pilot scale bioreactors and primary recovery equipment.
To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to . Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. EOEEstimated Salary: $20 to $28 per hour based on qualifications.
Ambrx, Inc. is a biopharmaceutical company with a mission to deliver breakthrough protein therapeutics using an expanded genetic code. Unlike conventional conjugation techniques that create a mixture of suboptimal molecules, Ambrx technology combines site specific conjugation with proprietary linkers, payloads and pharmacokinetic extenders to create a single molecular species that is optimized for safety, efficacy and biophysical properties. We call this process Protein Medicinal Chemistry
Ambrx is seeking a highly-motivated Scientist I/II to be a key member of a fast-paced and dynamic organization.
Responsibilities:
Responsible for developing cell culture medium, feeding strategies, process parameter optimization, and scale-up to support R&D, large scale production, pre-clinical, and clinical activities.
Participates in writing development reports, protocols, batch records and technology transfer.
Must demonstrate strong scientific/technical and interpersonal skills as well as the ability to communicate effectively.
Applies biological and engineering expertise to develop recombinant protein production processes suitable for large-scale cGMP manufacturing and acts as a mentor for those with similar or less engineering expertise, providing both technical expertise and leadership to understand potential career paths.
This job may require some travel to development partners and other manufacturing sites both in and outside the US. PhD with a minimum of 1
year(s) or Master's Degree with a minimum 8
years industrial experience and a degree in Chemical Engineering or related field.
Must have hands on experience in process development utilizing CHO cells to produce biologics using spin tubes, shake flasks, and bioreactors
Knowledgeable in cell culture process scale-up and technology transfer to contract manufacturing organizations.
Must have a proven record of innovation
Must have the ability to apply scientific and engineering principles to solve complex problems.
Must have a good understanding of cell physiology, metabolism, and cell biology
Must have the ability to multitask and adapt in a fast paced environment and stay focused on project deliverables.
Work with minimum supervision in designing and executing experiments and analyzing data.
Additional Desired Experience and Skills:
Knowledge of Design of Experiments (DOE) and statistical analysis of data.
Working knowledge of GMPs and experience writing SOPs and batch records.
Medium development experience for CHO cell culture
Experience with pilot scale bioreactors and primary recovery equipment.
To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to . Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. EOEEstimated Salary: $20 to $28 per hour based on qualifications.
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